PUBLICATIONS
i) Peer reviewed manuscripts
2021
75. Yang YB, Chan P, Rayani K, & McGirr A. Comparative Effectiveness of Repetitive Transcranial Magnetic Stimulation in Unipolar and Bipolar Depression. Can J Psychiatry. 2021 Mar;66(3):313-315.
74. Nguyen, TD, Hieronymus, F, Lorentzen, R, McGirr, A, & Østergaard, SA. The efficacy of repetitive transcranial magnetic stimulation (rTMS) for bipolar depression: A systematic review and meta-analysis. J. Affect. Disord. 2021; Jan 15;279(1):250-255.
73. Ismail, Z, McGirr, A, Gill, S, Hu, S, Forkert, ND, & Smith, EE. Mild Behavioral Impairment and Subjective Cognitive Decline Predict Cognitive and Functional Decline. J Alzheimers Dis. 2021; 80(1):459-469.
2020
72. Naude JP, Gill S, Hu S, McGirr A, Forkert ND, Monchi O, Stys PK, Smith EE, Ismail Z; Alzheimer’s Disease Neuroimaging Initiative. Plasma Neurofilament Light: A Marker of Neurodegeneration in Mild Behavioral Impairment. J Alzheimers Dis. 2020;76(3):1017-1027
71. McGirr, A, Devoe, DJ, Raedler, A, Debert, CT, Ismail, Z, & Berlim, MT. Repetitive Transcranial Magnetic Stimulation for the Treatment of Post-traumatic Stress Disorder: A Systematic Review and Network Meta-analysis. Can J Psychiatry. 2020; Dec 23.
70. Swainson, J, McGirr, A, Blier, P, Brietzke, E, Ravindran, N, Blier, J, Beaulieu, S, Frey, BN, Kennedy, SH, McIntyre, RS, Milev, RV, Parikh, SV, Schaffer, A, Taylor, VH, Tourjman, V, van Ameringen, M, Yatham, LN, Ravindran, AV, & Lam, RW. The Canadian Network for Mood and Anxiety Treatments (CANMAT) Task Force Recommendations for the Use of Racemic Ketamine in Adults with Major Depressive Disorder. Can J Psychiatry. 2020; Nov 11;66(2):113-125.
69. Leong K, Chan P, Ong L, Zwicker A, Willan S, Lam RW, McGirr A. A Randomized Sham-controlled Trial of 1-Hz and 10-Hz Repetitive Transcranial Magnetic Stimulation (rTMS) of the Right Dorsolateral Prefrontal Cortex in Civilian Post-traumatic Stress Disorder. Can J Psychiatry. 2020 Nov;65(11):770-778
68. Kopala-Sibley, D, Chartier, GB, Bhanot, S, Cole, J, Chan, PY, Berlim, MT, & McGirr, A. Personality Trait Predictive Utility and Stability in Transcranial Magnetic Stimulation (rTMS) for Major Depression: Dissociation of Neuroticism and Self-Criticism. Can J Psychiatry. 2020; 65(4):264-272.
67. McGirr, A*, LeDue, J, Chan, AW, Boyd, JD, Metzak, PD, Murphy, TH. Stress impacts sensory variability through cortical sensory activity motifs. Transl Psychiatry. 2020; Jan 21;10(1):20.
2019
66. Ashby, DM, LeDue, J, Murphy, TH, McGirr, A*. Peripheral Nerve Ligation Elicits Widespread Alterations in Cortical Sensory Evoked and Spontaneous Activity. Scientific Reports. 2019; Oct 25;9(1):15341.
65. Cole, J, Bright, K, Gagnon, L, McGirr, A. A systematic review of the safety and effectiveness of repetitive transcranial magnetic stimulation in the treatment of peripartum depression. J Psychiatric Res. 2019; 115:142-150.
64. Selby, B, MacMaster, F, Kirton, A, McGirr, A. D-Cycloserine blunts motor cortex facilitation after intermittent theta burst transcranial magnetic stimulation: a double-blind randomized placebo-controlled crossover study. Brain Stimulation. 2019; 12(4): 1063-65.
2018
63. Keramatian, K, Dhanoa, T, McGirr, A, Lang, DJ, Honer, WG, Lam, RW, & Yatham, LN. Structural Brain Changes in First Episode Mania with and without Psychosis: Data from Systematic Treatment Optimization Program for Early Mania (STOP-EM). World J Biol Psychiatry. 2018; 19(sup2):S30-40.
62. McGirr, A. & Berlim, MT. Efficacy and acceptability of neuromodulation in Major Depression: a systematic meta-review of meta-analyses. Psychiatr Clin North Am. 2018; 41(3): 485-503.
2017
61. Berlim, MT, McGirr, A, Tremlay, S, & Martins, R. Efficacy and acceptability of theta burst stimulation (TBS) for major depression: An exploratory meta-analysis of randomized and sham-controlled trials. J Psychiatric Res. 2017; 90: 102-109.
60. McGirr, A*, Berlim, MT, Bond, DJ, Chan, PY, Yatham, LN, & Lam, RW. An updated systematic review and meta-analysis of randomized controlled trials of adjunctive ketamine in electroconvulsive therapy. British J Psychiatry. 2017; 210(6):403-407.
59. McGirr, A*, LeDue, J, Chan, AW, Xie, Y, & Murphy, TH. Cortical functional hyper-connectivity in a mouse model of depression and selective network effects of ketamine. Brain. 2017; 140(8):2210-2225.
58. Tovar-Perdomo, S, McGirr, A, Van den Eynde, F, Rodrigues dos Santos, N, Berlim, MT. High frequency repetitive transcranial magnetic stimulation treatment for major depression: dissociated effects on psychopathology and neurocognition. J Affect Disord. 2017; 217: 112-117.
2016
57. Kozicky, J-M, McGirr, A, Bond, DJ, Gonzalez, M, Silveira, LE, Karamatian, K, Torres, IJ, Lam, RW, & Yatham, LN. Neuroprogression and episode recurrence in Bipolar I Disorder: a study of grey matter volume changes in first episode mania and association with clinical outcome. Bipolar Disorders. 2016; 18(6): 511-19.
56. McGirr, A* & Cusimano, MD. Does idiopathic Normal Pressure Hydrocephalus (iNPH) run in families? J Neurol Sci. 2016; 368: 128-9.
55. McGirr, A*, Karmani, S, Arsappa, R, Berlim, MT, Thirthalli, J, Muralidharan, K, Yatham, LN. The clinical efficacy and safety of repetitive transcranial magnetic stimulation (rTMS) in bipolar depression: a systematic review and meta-analysis of patients with bipolar disorder included in randomized, double-blind, and sham-controlled trials. World Psychiatry. 2016; 15(1): 85-6.
54. McGirr, A*, Lipina, TV, Mun, H-S, Georgiou, J, Ng, E, Zhai, D, Elliott, C, Cameron, RT, Mullins, JGL, Liu, F, Baillie, GS, Clapcote, S, Roder JC. Specific inhibition of phosphodiesterase-4B results in anxiolysis and facilitates memory acquisition. Neuropsychopharmacology. 2016; 41(4): 1080-92.
53. McGirr, A*, Vohringer, P, Ghaemi, SN, Lam, RW & Yatham, LN. The safety and efficacy of adjunctive modern antidepressant therapy with a mood stabilizer or antipsychotic in acute bipolar depression: A meta-analysis of randomized placebo controlled trials. Lancet Psychiatry. 2016; 3(12): 1138-46.
52. Xie, Y, Chan, AW, McGirr, A, Xue, S, Xiao, D, Zeng, H, & Murphy, TH. Resolution of high-frequency mesoscale intracortical maps using the genetically encoded glutamate sensor – iGluSnFR. Journal of Neuroscience. 2016; 36(4): 1261-72.
51. Xu, Y, Hackett, M, Carter, G, Loo, C, Galvez, V, Glozier, N, Glue, P, Lapidus, K, McGirr, A, Somogyi, A, Mitchell, PB, & Rodgers, A. Immediate and short-term effects of a single dose of ketamine among patients with major depression: a systematic review. Int J Neuropsychopharmacology. 2016; 19(4): 1-15.
2015
50. Gignac, A, McGirr, A, Lam, RW, & Yatham, LN. Course and outcome following a first episode of mania: four-year prospective data from the Systematic Treatment Optimization Program (STOP-EM). J Affect Disord. 2015; 175C: 411-417.
49. Gignac, A, McGirr, A, Lam, RW, & Yatham, LN. Recovery and recurrence following a first-episode of mania: a systematic review and meta-analysis of prospectively characterized cohorts. J Clin Psychiatry. 2015; 76(9): 1241-8.
48. McGirr, A*. The safety and efficacy of adjunctive ketamine in electroconvulsive therapy: Response to Drs. Fond and Boyer. J Psychiatric Res. 2015; 68: 283-284.
47. McGirr, A*, Berlim, MT, Bond, DJ, Fleck, MP, Yatham, LN, Lam, RW. A meta-analysis of randomized double-blind controlled trials of ketamine in the rapid treatment of major depressive episodes. Psychological Medicine. 2015; 45: 693-704.
46. McGirr, A*, Berlim, MT, Bond, DJ, Neufeld, NH, Chan PY, Yatham, LN, & Lam, RW. A systematic review and meta-analysis of randomized controlled trials of adjunctive ketamine in electroconvulsive therapy: efficacy and tolerability. J Psychiatric Res. 2015; 62: 23-30.
45. McGirr, A*, Berlim, MT, Bond, DJ, Neufeld, NH, Chan PY, Yatham, LN, & Lam, RW. Corrigendum to “A systematic review and meta-analysis of randomized controlled trials of adjunctive ketamine in electroconvulsive therapy: efficacy and tolerability” [J Psychiatr Res (2015) 62: 23-30]. J Psychiatric Res. 2015; 68: 74-75.
44. McGirr, A., Van den Eynde, F, Tovar-Perdomo, S, Fleck, MP, & Berlim, MT. Effectiveness and acceptability of accelerated repetitive transcranial magnetic stimulation (rTMS) for treatment-resistant Major Depressive Disorer: an open label trial. J Affect Disord. 2015; 173: 216-20.
43. Mun, HS, Saab, BJ, Ng, E, McGirr, A, Lipina, TV, Gondo, Y, Georgiou, J, & Roder, JC. Exploration of safe and novel space invokes a learning bonus in mice that requires NCS-1. Sci Reports.2015; Dec 7;5:17697. doi: 10.1038/srep17697.
42. Ouellet, J, McGirr, A, Jollant, F, Lepage, M, Van den Eynde, F, & Berlim, MT. Enhancing Decision-Making and Impulse Control with Transcranial Direct Current Stimulation (tDCS) of the Orbitofrontal Cortex (OFC): A Randomized and Sham-Controlled Study. J Psychiatric Res. 2015; 69: 27-34.
2014
41. Berlim, MT, McGirr, A., Van den Eynde, F, Fleck MP, Giacobbe, P. Effectiveness and acceptability of deep brain stimulation (DBS) of the subgenual cingulate cortex for treatment resistant depression: a systematic review and exploratory meta-analysis. J Affect Disord. 2014; 159: 31-8.
40. McGirr, A, & Bond, DJ. Comprehensive pharmacological management of bipolar depression. Curr Treat Options Psychiatry. 2014; 1(3): 263-77.
39. McGirr, A, Davis, L, Vila-Rodriguez, F. Idiopathic Burning Mouth Syndrome: a common treatment refractory somatoform condition responsive to ECT. Psychiatry Res. 2014; 216(1): 158-9.
38. McGirr, A*, Pavenski, K, Sharma, B & Cusimano, M. Blood conservation in neurosurgery: erythropoietin and autologous donation. Can J Neurol Sci. 2014; 41(5): 583-89.
37. McGirr, A, Van den Eynde, F, Chachamovich, E, Fleck, MP, Berlim, MT. Personality Dimensions and Deep Repetitive Transcranial Magnetic Stimulation (DTMS) for Treatment-Resistant Depression: A Pilot Trial on Five-Factor Prediction of Antidepressant Response. Neurosci Lett. 2014; 563: 144-8.
36. Vila-Rodriguez, F, McGirr, A, Tham, J, Hadjipavlou, G, Honey, CR. Electroconvulsive therapy in patients with deep brain stimulators. J ECT. 2014; 30(3): e16-18.
2013
35. Berlim, MT, McGirr, A, Beaulieu, M-A, Turecki, G. Neuroticism, extraversion and the antidepressant effects of repetitive transcranial magnetic stimulation: a prospective 4-week pilot study. Neurosci Lett. 2013; 534: 306-10.
34. Dalca, I, McGirr, A, Renaud, J, Turecki, G. Gender-specific suicide risk factors: a case-control study of individuals with major depressive disorder. J Clin Psychiatry. 2013; 74(12):1209-16.
33. Hovington, C, McGirr, A, Lepage, M, Berlim MT. Repetitive transcranial magnetic stimulation (rTMS) for treating major depression and schizophrenia: a systematic review of recent meta-analyses. Ann Med. 2013; 45(4):308-21.
32. McGirr, A & Cusimano, M. Unmet Tangible Social Support Needs in Idiopathic Normal Pressure Hydrocephalus. Can J Neurol Sci. 2013; 40(1):94-6.
31. McGirr, A, Jollant F, & Turecki, G. Neurocognitive Alterations in First Degree Relatives of Suicide Completers. J Affect Disord. 2013; 145(2):264-9.
30. McGirr, A, Mohammed, S, Cusimano, M. Clinical equipoise in Idiopathic Normal Pressure Hydrocephalus: a survey of physicians on the need for a randomized controlled trial assessing the efficacy of cerebrospinal fluid diversion. J Neurol Sci. 2013; 333(1-2):13-8.
29. Ng, E, McGirr, A, Wong, AHC, Roder JC. Using rodents to model schizophrenia and substance use comorbidity. Neurosci Biobehav Rev. 2013; 37(5): 896-910.
2012
28. Berlim, MT, McGirr, A, Beaulieu, M-A, Turecki, G. Theory of Mind in Subjects with Major Depressive Disorder: Is it Influenced by Repetitive Transcranial Magnetic Stimulation? World J Biol Psychiatry. 2012; 13(6): 474-9.
27. Lipina, TV, Haque FN, McGirr A, Mesbah-Oskui L, Boutros P, Roder JC, Wong, AH. Prophylactic valproic acid treatment prevents schizophrenia-related behaviour in Disc1-L100P mutant mice. PLoS One. 2012; 7(12): e51562.
26. McGirr, A, Cusimano MD. Familial aggregation of idiopathic normal pressure hydrocephalus: Novel familial case and a family study of the NPH triad in an iNPH patient cohort. J Neurol Sci. 2012; 312(1-2): 82-8.
25. McGirr, A, Dombrovski, A, Butters, MA, Clark, L, Szanto, K. Deterministic learning and attempted suicide among older depressed individuals: cognitive assessment using the wisconsin card sorting task. J Psychiatric Res. 2012; 46(2): 226-32.
2011
24. McGirr, A, Diaconu, G, Berlim, MT, Turecki G. Personal and Family History of Suicidal Behaviour are Associated With Lower Peripheral Cortisol In Depressed Outpatients. J Affect Disord. 2011; 131(1-3): 368-73.
23. Berlim, MT, McGirr, A, Beaulieu, M-A, Turecki, G. High frequency repetitive transcranial magnetic stimulation in highly treatment resistant major depression: a prospective 4-week naturalistic study. J Affect Disord. 2011; 130(1-2): 312-7.
22. Tousignant, M., Pouliot, L., Routhier, D., Vrakas, G., McGirr, A., & Turecki, G. Suicide, schizophrenia, and schizoid-type psychosis: the role of life events and childhood factors. Suicide and Life-Threatening Behaviour 2011; 41(1): 66-78.
2010
21. McGirr, A., Diaconu, G, Berlim, MT, Pruessner, JC, Sablé, R, Cabot, S, & Turecki, G. Dysregulation of the sympathetic nervous system, hypothalamic-pituitary-adrenal axis and executive function in individuals at risk for suicide. J Psychiatry & Neuroscience 2010; 35(6):399-408.
20. Renaud J, Berlim MT, Begolli, M, McGirr A, Turecki G. Sexual Orientation and Gender Identity in Youth Suicide Victims: An Exploratory Study. Can J Psychiatry 2010; 55(1): 29-34.
19. Séguin, M, Lesage, A, Boyer, R, McGirr, A, Suissa, A, Tousignant, M, Turecki, G. Suicide and gambling: Psychopathology and treatment-seeking. Psychology of Addictive Behaviors; (2010) 24(3): 541-7.
2009
18. McGirr, A, Alda, M, Séguin, M, Cabot, S, Lesage, A., Turecki, G. Familial Aggregation of Suicide Explained by Cluster B Traits: A Three-Group Family Study of Suicide Controlling for Major Depressive Disorder. Am J Psychiatry 2009; 166(10): 1124-1134.
17. McGirr, A, Paris, J., Lesage, A., Renaud, J., Turecki, G. An examination of DSM-IV borderline personality disorder symptoms and risk for suicide completion: a psychological autopsy study. Can J Psychiatry 2009; 54(2), 87-92.
16. McGirr, A & Turecki, G. Self-critical perfectionism is associated with increases in sympathetic indicators in a controlled laboratory stress paradigm. Psychosomatic Med 2009; 71(5): 588.
15. Renaud, J., Berlim, MT, Seguin, M., McGirr, A., Tousignant, M., Turecki, G. Recent and Lifetime Utilization of Health Care Services by Children and Adolescent Suicide Victims: A Case-Control Study. J Affect Dis. 2009 117(3): 168-173.
2008
14. McGirr, A., Renaud, J., Seguin, M., Alda, M., Turecki, G. Course of Major Depressive Disorder and Suicide Outcome. J Clin Psychiatry (2008); 69(6): 966-70.
13. McGirr A, Turecki G: What is specific to suicide in schizophrenia? Behavioural, clinical and sociodemographic dimensions. Schizophr Res 2008; 98(1-3):217-24.
12. McGirr A, Renaud J, Bureau A, Seguin M, Lesage A, Turecki G: Impulsive-aggressive behaviours and completed suicide across the life cycle: a predisposition for younger age of suicide. Psychological Medicine 2008; 38(3):407-17.
11. Berlim MT, McGirr A, Fleck MP. Can socio-demographic and clinical variables predict the quality of life of outpatients with major depression? Psychiatry Res 2008 160(3): 64-371.
10. Renaud J, Berlim MT, McGirr A, Tousignant M, Turecki G: Current psychiatric morbidity, aggression/impulsivity, and personality dimensions in child and adolescent suicide: A case-control study. J Affect Disord 2008; 105(1-3):221-8.
2007
9. McGirr A, Turecki G: The relationship of impulsive aggressiveness to suicidality and other depression-linked behaviors. Curr Psychiatry Rep 2007; 9(6):460-6.
8. McGirr, A., Paris, J., Lesage, A., Renaud, J., Turecki, G. Risk factors for suicide completion in borderline personality disorder: a case-control study of cluster B comorbidity and impulsive aggression. J Clin Psychiatry 2007; 68(5), 721-729.
7. McGirr, A., Renaud, J., Seguin, M., Alda, M., Benkelfat, C., Lesage, A., Turecki, G. An examination of DSM-IV depressive symptoms and risk for suicide completion in major depressive disorder: a psychological autopsy study. J Affect Disord 2007; 97(1), 203-209.
6. Abela, J. R., McGirr, A. Operationalizing cognitive vulnerability and stress from the perspective of the hopelessness theory: A multi-wave longitudinal study of children of affectively ill parents. Br J Clin Psychol 2007; 46(Pt 4), 377-395.
5. Abela, J. R., McGirr, A., Skitch, S. A. (2007). Depressogenic inferential styles, negative events, and depressive symptoms in youth: an attempt to reconcile past inconsistent findings. Behav Res Ther 2007; 45(10), 2397-2406.
4. Zouk, H., McGirr, A., Lebel, V., Benkelfat, C., Rouleau, G., Turecki, G. The effect of genetic variation of the serotonin 1B receptor gene on impulsive aggressive behavior and suicide. Am J Med Genet B Neuropsychiatr Genet 2007; 44(8), 996-1002.
2006
3. McGirr, A., Seguin, M., Renaud, J., Benkelfat, C., Alda, M., Turecki, G. Gender and risk factors for suicide: evidence for heterogeneity in predisposing mechanisms. J Clin Psychiatry 2006; 67, 1612-1617.
2. McGirr, A., Tousignant, M., Routhier, D., Pouliot, L., Chawky, N., Margolese, H. C., Turecki, G. Risk factors for completed suicide in schizophrenia and other chronic psychotic disorders: a case-control study. Schizophr Res 2006; 84(1), 132-143.
1. Renaud, J., Chagnon, F., Balan, B., Turecki, G., McGirr, A., Marquette, C. Psychiatric services utilization in completed suicides of a youth centres population. BMC Psychiatry 2006; 6, 36.
ii) Non-peer reviewed manuscripts
3. McGirr, A* & Cusimano, MD. Does idiopathic Normal Pressure Hydrocephalus (iNPH) run in families? J Neurol Sci. 2016; 368: 128-9.
2. Neufeld, NH, Sharma, B, McGirr, A*. Debates in Medicine: Global representation of medical discourse. The Lancet. 2014; 383: 779.
1. Neufeld, NH, Sharma, B, McGirr, A*. Sex disparity in academic medical discourse. BMJ Careers. http://careers.bmj.com/careers/advice/view-article.html?id=20018422
iii) Books, chapter
5. Desilets, A, Labossiere, M, McGirr, A, & Turecki, G. (2016) Schizophrenia, other psychotic disorders and suicidal behavior. In: O’Connor, R, Platt, S, & Gordon, J editors. International Handbook of Suicide Prevention, John Wiley & Sons, p93
4. McGirr, A, Vila-Rodriguez, F, Cusimano, M. (2014) Normal Pressure Hydrocephalus: etiology, diagnosis, treatment and putative nutritional and lifestyle risk factors. In: Martin, CR, Preedy, V. editors. Diet and Nutrition in Dementia and Cognitive Decline, Elsevier, p101-112.
3. McGirr, A. & Turecki, G. (2011) Schizophrenia, other psychotic disorders and suicidal behavior. In: O’Connor, R, Platt, S, & Gordon, J editors. International Handbook of Suicide Prevention: Research, Policy and Practice, Wiley-Blackwell, p75-93.
2. McGirr, A. (2009) [The Genetics of Suicide] In : Séguin, M editor. Le Suicide: le comprendre pour le prévenir. Montreal, Canada : Éditions au Carré, p160.
1. McGirr A, Berlim MT, Turecki G (2009): [The Genetics of Depression]. In: Tavares de Lacerda AL, de Castro Quarantini L, Miranda-Scippa AMA, Del Porto JA editors. Depressao. Porto Alegre, Brazil: Artmed Editora S.A., pp 191-205.